Mitochondria: multifaceted regulators of aging
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چکیده
منابع مشابه
Multifaceted aging and rapamycin
Aging is commonly defined as a time-dependent loss of physiological integrity, leading to the decline and impair in organism functions and to the increase of risk for cancer and other major age-associated diseases, finally increasing vulnerability to death [1]. During the last decade the intensive search of anti-aging remedies has lead to the conclusion that both the insulin/IGF-like signaling ...
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The free radical theory of aging postulates that the production of intracellular reactive oxygen species is the major determinant of life span. Numerous cell culture, invertebrate, and mammalian models exist that lend support to this half-century-old hypothesis. Here we review the evidence that both supports and conflicts with the free radical theory and examine the growing link between mitocho...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2019
ISSN: 1976-670X
DOI: 10.5483/bmbrep.2019.52.1.300